Dead and Company follows U2, closing in March, and Phish at the Sphere.
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The new spot, on South Water Street, will offer wine retail, tasting, flights and classes (plus coffee during the day).
The Las Vegas venue has been home to U2 and also will host Phish.
The new spot occupies the former Donut Bar on South Sixth Street with a menu that mixes doughnut holes and classic, fancy and specialty doughnuts.
The red-sauce Italian spot, originally on the Strip for 15 years, is also serving at an invite-only pop-up during Super Bowl week.
Calvin Harris plays LIV at Fontainebleau after the Super Bowl on Feb. 11.
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